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Tesamorelin 10mg

Tesamorelin is a synthetic growth hormone–releasing hormone (GHRH) analog studied in experimental models for its interaction with the hypothalamic–pituitary axis, particularly in stimulating endogenous growth hormone secretion. In clinical and research settings, tesamorelin has been investigated for its potential effects on metabolic processes, including lipid metabolism, body composition, and insulin-like growth factor-1 (IGF-1) modulation. Ongoing research explores how this peptide may influence pathways involved in adipose tissue regulation, glucose homeostasis, and endocrine signaling within controlled experimental contexts.

Original price was: $190.00.Current price is: $140.00.

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What Is Tesamorelin?

Tesamorelin is a synthetic peptide investigated in experimental and clinical research as an analog of growth hormone-releasing hormone (GHRH). It functions as an agonist of the growth hormone-releasing hormone receptor (GHRHR), enabling researchers to study signaling pathways involved in growth hormone secretion, endocrine regulation, and metabolic processes.

In laboratory and clinical investigations, tesamorelin has been examined as a research tool for exploring mechanisms associated with growth hormone dynamics, insulin-like growth factor-1 (IGF-1) signaling, lipid metabolism pathways, and endocrine system regulation. Through selective activation of the GHRH receptor, the peptide provides a model for studying how hypothalamic–pituitary signaling influences systemic metabolic and hormonal processes.

Across experimental models and controlled clinical investigations, tesamorelin has been associated with measurable changes in endocrine and metabolic parameters commonly monitored in research environments, including circulating growth hormone markers, IGF-1 signaling responses, lipid metabolism indicators, and adipose tissue regulatory pathways. These observations are interpreted through receptor-mediated endocrine signaling mechanisms rather than as outcomes or claims of applied use.

Tesamorelin Structure

Peptide Class: Growth hormone-releasing hormone (GHRH) analog
Receptor Target: Growth hormone-releasing hormone receptor (GHRHR)
Molecular Formula: C221H366N72O67S
Molecular Weight: ~5135 g/mol
CAS Number: 218949-48-5
Synonyms: tesamorelin, TH9507, Egrifta (research context)

Tesamorelin is engineered as a stabilized analog of endogenous GHRH designed to activate receptors responsible for stimulating growth hormone secretion from the anterior pituitary. Structural modifications incorporated into the peptide improve resistance to enzymatic degradation compared with native GHRH peptides, allowing for extended biological activity in experimental systems.

These molecular characteristics allow researchers to investigate sustained endocrine signaling responses related to growth hormone secretion and downstream IGF-1 mediated metabolic pathways.

Source: PubChem

Source: PubChem

Tesamorelin Research

Tesamorelin is used in research investigating growth hormone regulatory mechanisms and endocrine signaling networks. Typical experimental applications include receptor activation assays that evaluate intracellular signaling cascades initiated through GHRH receptor engagement.

Laboratory studies commonly examine parameters such as:

  • growth hormone secretion dynamics
  • insulin-like growth factor-1 (IGF-1) signaling responses
  • pituitary endocrine signaling activity
  • lipid metabolism markers
  • adipose tissue regulatory pathways

In vivo research models are also used to investigate how stimulation of GHRH receptors influences systemic metabolic regulation, endocrine feedback loops, and energy metabolism signaling pathways.

These investigations allow researchers to explore how hypothalamic–pituitary signaling contributes to metabolic homeostasis and hormonal regulatory networks.

Referenced Citations

  1. [1] Falutz J, Allas S, Blot K, et al. Metabolic effects of a growth hormone-releasing factor in patients with HIV.
    https://pubmed.ncbi.nlm.nih.gov/17053356/

    [2] Falutz J, Mamputu JC, Potvin D, et al. Effects of tesamorelin on abdominal fat and metabolic parameters.
    https://pubmed.ncbi.nlm.nih.gov/20357363/

    [3] Stanley TL, Feldpausch M, Oh J, et al. Effects of tesamorelin on liver fat and metabolic parameters.
    https://pubmed.ncbi.nlm.nih.gov/25056883/

    [4] Bowers CY. Growth hormone-releasing hormone and its analogs.
    https://pubmed.ncbi.nlm.nih.gov/16503379/

    [5] PubChem. Tesamorelin compound summary.
    https://pubchem.ncbi.nlm.nih.gov/compound/Tesamorelin

    [6] FDA Drug Database. Tesamorelin overview and pharmacology.
    https://www.ncbi.nlm.nih.gov/books/NBK547852/

Storage Instructions:

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.

Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you’re ready to reconstitute it with bacteriostatic water.

Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.

However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.

For further information on proper storage techniques, click the link below:

Peptide Storage

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