Selank 10mg
Selank is a synthetic heptapeptide analog studied for its role in neuromodulation, particularly within anxiety, cognition, and immune signaling pathways. This 10mg vial contains high-purity lyophilized Selank for controlled laboratory research. Precision neuro-modulation research peptide, clean signal, no heavy sedation profile, ideal for cognitive and stress-response studies.
Original price was: $78.00.$60.00Current price is: $60.00.
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Overview
Selank is a synthetic heptapeptide derived from tuftsin, a naturally occurring immune-modulating peptide fragment. It has been investigated in experimental and translational research for its potential influence on neurotransmitter regulation, stress-response pathways, and neuroimmune signaling.
Originally developed through peptide research programs exploring neuroactive compounds, Selank has been studied for its interactions with pathways involved in anxiety regulation, cognitive function, and neurochemical balance.
Experimental literature has examined Selank in models assessing:
- stress-response signaling
- neurotransmitter modulation
- cognitive performance pathways
- neuroinflammation markers
- immune system peptide signaling
These studies explore how Selank may influence communication between the central nervous system and immune signaling networks.
Biochemical Characteristics
Peptide Class
Synthetic heptapeptide derived from tuftsin
Amino Acid Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular Formula
C₃₃H₅₇N₁₁O₉
Molecular Weight
751.9 g/mol
Selank was designed by modifying the natural immune peptide tuftsin, extending its sequence to increase stability and prolong biological activity in experimental systems.
Research Applications
Selank has been studied primarily in neurobiology and psychophysiology research. Experimental investigations commonly explore its influence on neurotransmitter systems and stress-related signaling pathways.
Neurotransmitter Studies
Research models have explored potential interactions with systems such as:
- GABAergic signaling
- serotonergic pathways
- dopaminergic activity
These pathways are central to processes involved in mood regulation, emotional response, and cognitive function.
Cognitive and Behavioral Models
Laboratory studies have investigated Selank in experimental settings measuring:
- memory performance
- attention and learning models
- stress resilience
- behavioral response under anxiety-inducing conditions
Neuroimmune Research
Because of its origin from tuftsin, Selank has also been examined in studies analyzing:
- cytokine signaling patterns
- immune-modulatory peptide activity
- neuroimmune communication pathways
Referenced Citations
A. A. Zozulya, M. A. Volkova, G. G. Neznamov, and N. F. Myasoedov, “Effect of the synthetic peptide Selank on the expression of genes involved in neurotransmission in the rat brain,” Bull. Exp. Biol. Med., vol. 145, no. 3, pp. 336–338, 2008. [PubMed]
M. A. Volkova, A. A. Zozulya, and N. F. Myasoedov, “Effect of Selank on cytokine gene expression and immune response mechanisms,” Bull. Exp. Biol. Med., vol. 146, no. 2, pp. 231–234, 2008. [PubMed]
L. A. Andreeva, N. F. Myasoedov, and G. G. Neznamov, “Influence of the synthetic peptide Selank on monoamine neurotransmitter systems in the brain,” Neurosci. Behav. Physiol., vol. 39, no. 6, pp. 569–573, 2009. [PubMed]
G. G. Neznamov and E. S. Teleshova, “Comparative clinical study of Selank and benzodiazepines in anxiety disorders,” Neurosci. Behav. Physiol., vol. 39, no. 4, pp. 367–372, 2009. [PubMed]
A. A. Zozulya, M. A. Volkova, and N. F. Myasoedov, “Effects of the peptide Selank on GABAergic neurotransmission and behavioral anxiety models,” Bull. Exp. Biol. Med., vol. 147, no. 1, pp. 95–97, 2009. [PubMed]
M. A. Volkova, A. A. Zozulya, and N. F. Myasoedov, “Selank modulates cytokine gene expression and neuroimmune regulatory pathways,” Bull. Exp. Biol. Med., vol. 150, no. 4, pp. 452–455, 2010. [PubMed]
L. A. Andreeva, A. A. Zozulya, and N. F. Myasoedov, “Neuropeptide Selank and its influence on stress-response mechanisms in experimental models,” Neurosci. Behav. Physiol., vol. 41, no. 1, pp. 89–94, 2011. [PubMed]
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| Properties | |
|---|---|
| Molecular Formula | C37H51N9O10S |
| Molecular Weight | 813.9 |
| Monoisotopic Mass | 813.34796003 |
| Polar Area | 312 |
| Complexity | 1450 |
| XLogP | -2.8 |
| Heavy Atom Count | 57 |
| Hydrogen Bond Donor Count | 8 |
| Hydrogen Bond Acceptor Count | 13 |
| Rotatable Bond Count | 21 |
| PubChem LCSS | ACTH (4-7), Pro-Gly-Pro- Laboratory Chemical Safety Summary |
| Identifiers | |
|---|---|
| CID | 9811102 |
| InChI | InChI=1S/C37H51N9O10S/c1-57-16-13-24(38)32(50)42-25(11-12-31(48)49)33(51)43-26(18-23-19-39-21-41-23)34(52)44-27(17-22-7-3-2-4-8-22)36(54)46-15-5-9-28(46)35(53)40-20-30(47)45-14-6-10-29(45)37(55)56/h2-4,7-8,19,21,24-29H,5-6,9-18,20,38H2,1H3,(H,39,41)(H,40,53)(H,42,50)(H,43,51)(H,44,52)(H,48,49)(H,55,56)/t24-,25-,26-,27-,28-,29-/m0/s1 |
| InChIKey | AFEHBIGDWIGTEH-AQRCPPRCSA-N |
| Isometric SMILES | CSCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N3CCC[C@H]3C(=O)NCC(=O)N4CCC[C@H]4C(=O)O)N |
| Canonical SMILES | CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)N3CCCC3C(=O)NCC(=O)N4CCCC4C(=O)O)N |
| IUPAC Name | (2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-4-carboxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid |
Storage Instructions:
All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.
Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you’re ready to reconstitute it with bacteriostatic water.
Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.
However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.
For further information on proper storage techniques, click the link below:
Peptide Storage