{"id":703,"date":"2025-12-24T15:16:50","date_gmt":"2025-12-24T15:16:50","guid":{"rendered":"https:\/\/biovantixlab.com\/?post_type=product&#038;p=703"},"modified":"2026-07-13T20:47:58","modified_gmt":"2026-07-13T20:47:58","slug":"slu-pp-332-10mg","status":"publish","type":"product","link":"https:\/\/md.biovantixlab.com\/?product=slu-pp-332-10mg","title":{"rendered":"SLU-PP-332  10MG"},"content":{"rendered":"\t\t<div data-elementor-type=\"product-post\" data-elementor-id=\"703\" class=\"elementor elementor-703\" data-elementor-post-type=\"product\">\n\t\t\t\t<div class=\"elementor-element elementor-element-631530f e-con-full e-flex e-con e-parent\" data-id=\"631530f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6409263 e-n-tabs-mobile elementor-widget elementor-widget-n-tabs\" data-id=\"6409263\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;tabs_justify_horizontal&quot;:&quot;start&quot;,&quot;horizontal_scroll&quot;:&quot;disable&quot;}\" data-widget_type=\"nested-tabs.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-tabs\" data-widget-number=\"104895075\" aria-label=\"Tabs. Open items with Enter or Space, close with Escape and navigate using the Arrow keys.\">\n\t\t\t<div class=\"e-n-tabs-heading\" role=\"tablist\">\n\t\t\t\t\t<button id=\"e-n-tab-title-1048950751\" data-tab-title-id=\"e-n-tab-title-1048950751\" class=\"e-n-tab-title\" aria-selected=\"true\" data-tab-index=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"e-n-tab-content-1048950751\" style=\"--n-tabs-title-order: 1;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tDescription\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"e-n-tabs-content\">\n\t\t\t\t<div id=\"e-n-tab-content-1048950751\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1048950751\" data-tab-index=\"1\" style=\"--n-tabs-title-order: 1;\" class=\"e-active elementor-element elementor-element-897d6be e-con-full e-flex e-con e-child\" data-id=\"897d6be\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-44b9fba e-flex e-con-boxed e-con e-child\" data-id=\"44b9fba\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b926133 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"b926133\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#1\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>1. <\/span>SLU-PP-332 Overview<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#2\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>2. <\/span>SLU-PP-332 Structure<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-971ce9b elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"971ce9b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#3\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>3. <\/span>SLU-PP-332 Research<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#4\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>4. <\/span>SLU-PP-332 References<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a49f79b e-flex e-con-boxed e-con e-child\" data-id=\"a49f79b\" data-element_type=\"container\" data-e-type=\"container\" id=\"1\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8d0502c e-con-full e-flex e-con e-child\" data-id=\"8d0502c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-59aaf24 elementor-widget elementor-widget-heading\" data-id=\"59aaf24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SLU-PP-332: Overview\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ee5a12a e-con-full e-flex e-con e-child\" data-id=\"ee5a12a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7b63b42 elementor-widget elementor-widget-text-editor\" data-id=\"7b63b42\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>SLU-PP-332 is a low-molecular-weight synthetic small molecule developed as a selective agonist of estrogen-related orphan receptors (ERRs), with primary activity at the ERR\u03b1 and ERR\u03b3 isoforms. Estrogen-related receptors are ligand-activated transcription factors that localize to the nucleus and regulate gene expression programs associated with cellular energy metabolism, mitochondrial biogenesis, and oxidative phosphorylation.<\/p><p>SLU-PP-332 has been characterized exclusively in preclinical research systems, including in-vitro cellular models and in-vivo animal studies, where it is used as a molecular tool to interrogate ERR-dependent transcriptional networks and mitochondrial regulatory pathways.<\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-805a397 e-flex e-con-boxed e-con e-child\" data-id=\"805a397\" data-element_type=\"container\" data-e-type=\"container\" id=\"2\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-e03ab05 e-con-full e-flex e-con e-child\" data-id=\"e03ab05\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1eea56f elementor-widget elementor-widget-heading\" data-id=\"1eea56f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SLU-PP-332: Biochemical Characteristics\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c9269a6 e-con-full e-flex e-con e-child\" data-id=\"c9269a6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-819ee1e elementor-widget elementor-widget-image\" data-id=\"819ee1e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"444\" height=\"444\" src=\"https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-32.webp\" class=\"attachment-full size-full wp-image-692\" alt=\"\" srcset=\"https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-32.webp 444w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-32-300x300.webp 300w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-32-150x150.webp 150w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-32-100x100.webp 100w\" sizes=\"(max-width: 444px) 100vw, 444px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-313789c elementor-widget elementor-widget-text-editor\" data-id=\"313789c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div id=\"structure\" class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div id=\"structure\" class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>Source:\u00a0<a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/5338394#section=Names-and-Identifiers\" target=\"_blank\" rel=\"nofollow noopener\">PubChem<\/a><\/p><p><strong>Chemical Formula:<\/strong>\u00a0C18H14N2O2<br \/><strong>Molecular Weight:<\/strong>\u00a0290.3 g\/mol<br \/><strong>PubChem CID:<\/strong>\u00a05338394<br \/><strong>CAS No.:<\/strong>\u00a0303760-60-3<br \/><strong>Synonyms:<\/strong>\u00a04-Hydroxy-N&#8217;-(naphthalen-2-ylmethylene) benzohydrazide<\/p><p>SLU-PP-332 is chemically stable under standard laboratory conditions and has demonstrated intracellular nuclear accessibility in experimental systems, enabling direct modulation of ERR-mediated transcriptional activity.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-89a922c e-flex e-con-boxed e-con e-child\" data-id=\"89a922c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-f5455f0 e-con-full e-flex e-con e-child\" data-id=\"f5455f0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dd6fbb4 elementor-widget elementor-widget-heading\" data-id=\"dd6fbb4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SLU-PP-332: Research Applications\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cc49a3c e-con-full e-flex e-con e-child\" data-id=\"cc49a3c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f48ec5c elementor-widget elementor-widget-text-editor\" data-id=\"f48ec5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div id=\"research\" class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div id=\"biochem\" class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>SLU-PP-332 is supplied strictly for laboratory research use and has been employed in controlled experimental models to investigate:<\/p><ul><li>ERR\u03b1- and ERR\u03b3-dependent transcriptional regulation<\/li><li>Mitochondrial biogenesis and ultrastructural remodeling<\/li><li>Oxidative phosphorylation and fatty acid oxidation pathways<\/li><li>Cellular energy homeostasis and metabolic gene networks<\/li><li>Autophagy-associated transcriptional signaling<\/li><\/ul><p>All applications are limited to non-clinical, non-diagnostic experimental systems.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8f12065 e-flex e-con-boxed e-con e-child\" data-id=\"8f12065\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-67de5a3 e-con-full e-flex e-con e-child\" data-id=\"67de5a3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-49efd74 elementor-widget elementor-widget-heading\" data-id=\"49efd74\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SLU-PP-332: Pathway \/ Mechanistic Context\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fddb75a e-con-full e-flex e-con e-child\" data-id=\"fddb75a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d874b6d elementor-widget elementor-widget-text-editor\" data-id=\"d874b6d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div id=\"research\" class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>Estrogen-related receptors function as constitutively active transcription factors that bind ERR response elements within promoter regions of genes governing mitochondrial respiration, lipid metabolism, and oxidative stress regulation. SLU-PP-332 has been shown in preclinical models to enhance ERR\u03b1- and ERR\u03b3-mediated transcriptional output.<\/p><p>Downstream effects observed in experimental systems include increased expression of genes associated with electron transport chain assembly, mitochondrial fatty acid uptake, and transcription factor EB (TFEB)-regulated autophagy pathways. These effects position SLU-PP-332 as a mechanistic probe for studying mitochondrial quality control and energy regulation at the transcriptional level.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-855637d e-flex e-con-boxed e-con e-child\" data-id=\"855637d\" data-element_type=\"container\" data-e-type=\"container\" id=\"3\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3657e2d e-con-full e-flex e-con e-child\" data-id=\"3657e2d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-902f324 elementor-widget elementor-widget-heading\" data-id=\"902f324\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SLU-PP-332: Preclinical Research Summary\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5e8875f e-con-full e-flex e-con e-child\" data-id=\"5e8875f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7829a1 elementor-widget elementor-widget-text-editor\" data-id=\"c7829a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div id=\"mechanism\" class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>Preclinical investigations utilizing rodent and cellular models have demonstrated that SLU-PP-332 modulates ERR-dependent gene networks governing mitochondrial density, substrate utilization, and oxidative capacity. These studies report alterations in mitochondrial morphology, respiratory efficiency, and lipid oxidation under controlled experimental conditions.<\/p><p>Additional research has examined SLU-PP-332 in models of metabolic stress, cardiac energetic demand, renal mitochondrial aging, and neuronal mitochondrial maintenance, providing insight into conserved ERR-regulated bioenergetic pathways.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e9172de elementor-widget elementor-widget-image\" data-id=\"e9172de\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1024\" height=\"416\" src=\"https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-332-2-1024x416.webp\" class=\"attachment-large size-large wp-image-691\" alt=\"\" srcset=\"https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-332-2-1024x416.webp 1024w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-332-2-300x122.webp 300w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-332-2-768x312.webp 768w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-332-2-1536x624.webp 1536w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-332-2-600x244.webp 600w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2025\/12\/SLU-PP-332-2.webp 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-40ba7b7 e-flex e-con-boxed e-con e-child\" data-id=\"40ba7b7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-fa5e150 e-con-full e-flex e-con e-child\" data-id=\"fa5e150\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d98030c elementor-widget elementor-widget-heading\" data-id=\"d98030c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SLU-PP-332: Form &amp; Analytical Testing\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2f740c1 e-con-full e-flex e-con e-child\" data-id=\"2f740c1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d1c1164 elementor-widget elementor-widget-text-editor\" data-id=\"d1c1164\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div id=\"preclinical\" class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>SLU-PP-332 is supplied as a research-grade small molecule compound. Each lot is produced under controlled conditions and verified using standard analytical techniques, including chromatographic purity assessment and mass-based identity confirmation.<\/p><p>Analytical data are provided solely to support experimental reproducibility.<\/p><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-60414f8 e-flex e-con-boxed e-con e-child\" data-id=\"60414f8\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c7adcc9 e-con-full e-flex e-con e-child\" data-id=\"c7adcc9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4a989dd elementor-widget elementor-widget-heading\" data-id=\"4a989dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">About The Author\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-adfc704 e-con-full e-flex e-con e-child\" data-id=\"adfc704\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-eedc3a1 elementor-widget elementor-widget-text-editor\" data-id=\"eedc3a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>The above literature was researched, edited, and organized by Dr. Logan, M.D. Dr. Logan holds a doctorate degree from\u00a0<a href=\"https:\/\/case.edu\/medicine\/\" target=\"_blank\" rel=\"nofollow noopener\">Case Western Reserve University School of Medicine<\/a> and a B.S. in molecular biology.<\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6c4120a e-flex e-con-boxed e-con e-child\" data-id=\"6c4120a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-830fffb e-con-full e-flex e-con e-child\" data-id=\"830fffb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3ccdcba elementor-widget elementor-widget-heading\" data-id=\"3ccdcba\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Scientific Journal Author\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b6afb21 e-con-full e-flex e-con e-child\" data-id=\"b6afb21\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bb0f5a6 elementor-widget elementor-widget-text-editor\" data-id=\"bb0f5a6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p><a href=\"https:\/\/www.researchgate.net\/profile\/Hamid-Nasri\" target=\"_blank\" rel=\"nofollow noopener\">Dr. Hamid Nasri, M.D.,<\/a>\u00a0<span class=\"relative -mx-px my-[-0.2rem] rounded px-px py-[0.2rem]\">is a Clinical Nephropathologist and Nephrologist affiliated with the Department of Natural Sciences at The University of Georgia in Tbilisi, Georgia.<\/span>\u00a0<span class=\"relative -mx-px my-[-0.2rem] rounded px-px py-[0.2rem]\">He is also a retired Professor of Nephrology as of February 2024.<\/span><\/p><p>\u200b<span class=\"relative -mx-px my-[-0.2rem] rounded px-px py-[0.2rem]\">Dr. Hamid Nasri, M.D.,<\/span> is referenced as one of the leading scientists involved in the research and development of SLU-PP-332. In no way is this doctor\/scientist endorsing or advocating the purchase, sale, or use of this product for any reason. There is no affiliation or relationship, implied or otherwise, between Peptide Sciences and this doctor. The purpose of citing the doctor is to acknowledge, recognize, and credit the exhaustive research and development efforts conducted by the scientists studying this peptide. Dr.Hamid Nasri, M.D., is listed in [1] under the referenced citations.<\/p><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f9db3fd e-flex e-con-boxed e-con e-child\" data-id=\"f9db3fd\" data-element_type=\"container\" data-e-type=\"container\" id=\"4\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-73081e4 e-con-full e-flex e-con e-child\" data-id=\"73081e4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1a44bb2 elementor-widget elementor-widget-heading\" data-id=\"1a44bb2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Resources<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-550b787 e-con-full e-flex e-con e-child\" data-id=\"550b787\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e621c75 elementor-widget elementor-widget-text-editor\" data-id=\"e621c75\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><ol><li><a title=\"New hopes on \u201cSLU-PP-332\u201d as an effective agent for weight loss with indirect kidney protection efficacy; a nephrology point of view\" href=\"https:\/\/doi.org\/10.34172\/jre.2024.25143\" target=\"_blank\" rel=\"nofollow noopener\">H. Nasri, \u201cNew hopes on \u2018SLU-PP-332\u2019 as an effective agent for weight loss with indirect kidney protection efficacy; a nephrology point of view,\u201d J Ren Endocrinol, vol. 10, no. 1, Art. no. 1, Jan. 2024, doi: 10.34172\/jre.2024.25143.<\/a><\/li><li><a title=\"Loss of skeletal muscle estrogen-related receptors leads to severe exercise intolerance\" href=\"https:\/\/doi.org\/10.1016\/j.molmet.2023.101670\" target=\"_blank\" rel=\"nofollow noopener\">J.-S. Wattez et al., \u201cLoss of skeletal muscle estrogen-related receptors leads to severe exercise intolerance,\u201d Mol Metab, vol. 68, p. 101670, Jan. 2023, doi: 10.1016\/j.molmet.2023.101670.<\/a><\/li><li><a title=\"Endocrine-disrupting chemicals, epigenetics, and skeletal system dysfunction: exploration of links using bisphenol A as a model system \" href=\"https:\/\/doi.org\/10.1093\/eep\/dvy002\" target=\"_blank\" rel=\"nofollow noopener\">F. Xin, L. M. Smith, M. Susiarjo, M. S. Bartolomei, and K. J. Jepsen, \u201cEndocrine-disrupting chemicals, epigenetics, and skeletal system dysfunction: exploration of links using bisphenol A as a model system,\u201d Environ Epigenet, vol. 4, no. 2, p. dvy002, Apr. 2018, doi: 10.1093\/eep\/dvy002.<\/a><\/li><li><a title=\"Estrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy\" href=\"https:\/\/doi.org\/10.1038\/s41531-022-00369-w\" target=\"_blank\" rel=\"nofollow noopener\">S. N. Fox et al., \u201cEstrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy,\u201d npj Parkinsons Dis., vol. 8, no. 1, pp. 1\u201319, Aug. 2022, doi: 10.1038\/s41531-022-00369-w.<\/a><\/li><li><a title=\"Synthetic ERR\u03b1\/\u03b2\/\u03b3 Agonist Induces an ERR\u03b1-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity\" href=\"https:\/\/doi.org\/10.1021\/acschembio.2c00720\" target=\"_blank\" rel=\"nofollow noopener\">C. Billon et al., \u201cSynthetic ERR\u03b1\/\u03b2\/\u03b3 Agonist Induces an ERR\u03b1-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity,\u201d ACS Chem. Biol., vol. 18, no. 4, pp. 756\u2013771, Apr. 2023, doi: 10.1021\/acschembio.2c00720.<\/a><\/li><li><a title=\"Mimicking exercise: what matters most and where to next?\" href=\"https:\/\/doi.org\/10.1113\/JP278761\" target=\"_blank\" rel=\"nofollow noopener\">J. A. Hawley, M. J. Joyner, and D. J. Green, \u201cMimicking exercise: what matters most and where to next?,\u201d J Physiol, vol. 599, no. 3, pp. 791\u2013802, Feb. 2021, doi: 10.1113\/JP278761.<\/a><\/li><li><a title=\"Mimicking exercise with a pill\" href=\"https:\/\/www.acs.org\/pressroom\/presspacs\/2024\/march\/mimicking-exercise-with-a-pill.html\" target=\"_blank\" rel=\"nofollow noopener\">\u201cMimicking exercise with a pill,\u201d American Chemical Society. Accessed: Jan. 23, 2025. [Online]. Available: https:\/\/www.acs.org\/pressroom\/presspacs\/2024\/march\/mimicking-exercise-with-a-pill.html<\/a><\/li><li><a title=\"Weight loss: Exercise-mimicking drug may reduce fat, improve insulin\" href=\"https:\/\/www.medicalnewstoday.com\/articles\/new-drug-may-help-lose-weight-reduce-fat-by-mimicking-exercise\" target=\"_blank\" rel=\"nofollow noopener\">\u201cWeight loss: Exercise-mimicking drug may reduce fat, improve insulin.\u201d Accessed: Jan. 23, 2025. [Online]. Available: https:\/\/www.medicalnewstoday.com\/articles\/new-drug-may-help-lose-weight-reduce-fat-by-mimicking-exercise<\/a><\/li><li><a title=\"Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db\/db mice\" href=\"https:\/\/doi.org\/10.1038\/srep26442\" target=\"_blank\" rel=\"nofollow noopener\">P.-M. Badin et al., \u201cExercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db\/db mice,\u201d Sci Rep, vol. 6, no. 1, p. 26442, May 2016, doi: 10.1038\/srep26442.<\/a><\/li><li><a title=\"Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function\" href=\"https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.123.066542\" target=\"_blank\" rel=\"nofollow noopener\">W. Xu et al., \u201cNovel pan-ERR agonists ameliorate heart failure through enhancing cardiac fatty acid metabolism and mitochondrial function,\u201d Circulation, vol. 149, no. 3, pp. 227\u2013250, Jan. 2024, doi: 10.1161\/CIRCULATIONAHA.123.066542.<\/a><\/li><li><a title=\"The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB\" href=\"https:\/\/doi.org\/10.1124\/molpharm.124.000889\" target=\"_blank\" rel=\"nofollow noopener\">M. Losby et al., \u201cThe Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB,\u201d Mol Pharmacol, vol. 106, no. 4, pp. 164\u2013172, Sep. 2024, doi: 10.1124\/molpharm.124.000889.<\/a><\/li><li><a title=\"Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney\" href=\"https:\/\/doi.org\/10.1016\/j.ajpath.2023.07.008\" target=\"_blank\" rel=\"nofollow noopener\">X. X. Wang et al., \u201cEstrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney,\u201d Am J Pathol, vol. 193, no. 12, pp. 1969\u20131987, Dec. 2023, doi: 10.1016\/j.ajpath.2023.07.008.<\/a><\/li><li><a title=\"Mitochondrial dysfunction in cell senescence and aging\" href=\"https:\/\/doi.org\/10.1172\/JCI158447\" target=\"_blank\" rel=\"nofollow noopener\">S. Miwa, S. Kashyap, E. Chini, and T. von Zglinicki, \u201cMitochondrial dysfunction in cell senescence and aging,\u201d J Clin Invest, vol. 132, no. 13, p. e158447, Jul. 2022, doi: 10.1172\/JCI158447.<\/a><\/li><li><a title=\"A Selective ERR\u03b1\/\u03b3 Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells\" href=\"https:\/\/doi.org\/10.1021\/acschembio.0c00670\" target=\"_blank\" rel=\"nofollow noopener\">E. Schoepke et al., \u201cA Selective ERR\u03b1\/\u03b3 Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells,\u201d ACS Chem Biol, vol. 15, no. 9, pp. 2338\u20132345, Sep. 2020, doi: 10.1021\/acschembio.0c00670.<\/a><\/li><li><a title=\"Not committed to fail: novel approach improves heart failure outcomes in animal model\" href=\"https:\/\/blogs.bcm.edu\/2024\/02\/08\/from-the-labs-not-committed-to-fail-novel-approach-improves-heart-failure-outcomes-in-animal-model\/\" target=\"_blank\" rel=\"nofollow noopener\">A. Rodr\u00edguez, \u201cNot committed to fail: novel approach improves heart failure outcomes in animal model,\u201d Baylor College of Medicine Blog Network. Accessed: Jan. 23, 2025. [Online]<\/a><\/li><\/ol><p><strong>ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.<\/strong><\/p><p>The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.<\/p><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9d6ee45 e-flex e-con-boxed e-con e-child\" data-id=\"9d6ee45\" data-element_type=\"container\" data-e-type=\"container\" id=\"4\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-a2220ad e-con-full e-flex e-con e-child\" data-id=\"a2220ad\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c49541f elementor-widget elementor-widget-heading\" data-id=\"c49541f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">RUO Disclaimer\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b9f30db e-con-full e-flex e-con e-child\" data-id=\"b9f30db\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c2b5237 elementor-widget elementor-widget-text-editor\" data-id=\"c2b5237\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div id=\"product.info.description\" class=\"product-tab-content\" role=\"tabpanel\" aria-labelledby=\"tab-label-product.info.description\" data-role=\"content\" aria-hidden=\"false\"><div class=\"l-page__container description\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p><strong>For Laboratory Research Only. Not for human use, medical use, diagnostic use, or veterinary use.<\/strong><\/p><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>SLU-PP-332 is a small-molecule research compound identified as a selective peroxisome proliferator-activated receptor delta (PPAR\u03b4) agonist. In preclinical models, it has been shown to enhance fatty acid oxidation, mitochondrial biogenesis, and metabolic efficiency through the modulation of PPAR\u03b4-dependent gene expression. SLU-PP-332 is used in metabolic and mitochondrial research investigating lipid metabolism, endurance-related signaling, and cellular energy regulation mechanisms.<\/p>\n<p><strong>References:<\/strong><br \/>\nNarkar VA et al., <em>Cell<\/em>, 2008;134(3):405\u2013415<br \/>\nFan W et al., <em>Journal of Biological Chemistry<\/em>, 2004;279(7):5241\u20135248<br \/>\nBillon C et al., <em>Cell Metabolism<\/em>, 2022;34(1):69\u201384<\/p>\n<p>These capsules are supplied exclusively as inert containers for the transport, storage, and dry handling of laboratory research materials. They are not pharmaceutical dosage forms and are not intended for ingestion or administration. They must not be used as drug delivery systems, consumed, or administered in any manner.<\/p>\n<p>For research use only. Not for human or animal use. 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