{"id":1050,"date":"2026-01-29T15:09:06","date_gmt":"2026-01-29T15:09:06","guid":{"rendered":"https:\/\/biovantixlab.com\/?post_type=product&#038;p=1050"},"modified":"2026-07-13T20:48:01","modified_gmt":"2026-07-13T20:48:01","slug":"semax-10mg","status":"publish","type":"product","link":"https:\/\/md.biovantixlab.com\/?product=semax-10mg","title":{"rendered":"Semax 10mg"},"content":{"rendered":"\t\t<div data-elementor-type=\"product-post\" data-elementor-id=\"1050\" class=\"elementor elementor-1050\" data-elementor-post-type=\"product\">\n\t\t\t\t<div class=\"elementor-element elementor-element-631530f e-con-full e-flex e-con e-parent\" data-id=\"631530f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6409263 e-n-tabs-mobile elementor-widget elementor-widget-n-tabs\" data-id=\"6409263\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;tabs_justify_horizontal&quot;:&quot;start&quot;,&quot;horizontal_scroll&quot;:&quot;disable&quot;}\" data-widget_type=\"nested-tabs.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-tabs\" data-widget-number=\"104895075\" aria-label=\"Tabs. Open items with Enter or Space, close with Escape and navigate using the Arrow keys.\">\n\t\t\t<div class=\"e-n-tabs-heading\" role=\"tablist\">\n\t\t\t\t\t<button id=\"e-n-tab-title-1048950751\" data-tab-title-id=\"e-n-tab-title-1048950751\" class=\"e-n-tab-title\" aria-selected=\"true\" data-tab-index=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"e-n-tab-content-1048950751\" style=\"--n-tabs-title-order: 1;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tDescription\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-1048950752\" data-tab-title-id=\"e-n-tab-title-1048950752\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-1048950752\" style=\"--n-tabs-title-order: 2;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tChemical Properties\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-1048950753\" data-tab-title-id=\"e-n-tab-title-1048950753\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-1048950753\" style=\"--n-tabs-title-order: 3;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tStorage\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"e-n-tabs-content\">\n\t\t\t\t<div id=\"e-n-tab-content-1048950751\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1048950751\" data-tab-index=\"1\" style=\"--n-tabs-title-order: 1;\" class=\"e-active elementor-element elementor-element-897d6be e-con-full e-flex e-con e-child\" data-id=\"897d6be\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-44b9fba e-flex e-con-boxed e-con e-child\" data-id=\"44b9fba\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b926133 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"b926133\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#1\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>1. <\/span>Overview<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#2\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>2. <\/span>Biochemical Characteristics<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#2\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>3. <\/span>Research Applications<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-029a1c3 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"029a1c3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#4\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>4. <\/span>Preclinical Research Summary<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#5\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>5. <\/span>Form &amp; Analytical Testing<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#5\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>6. <\/span>Referenced Citations<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#5\">\n\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><span>7. <\/span>RUO Disclaimer<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a49f79b e-flex e-con-boxed e-con e-child\" data-id=\"a49f79b\" data-element_type=\"container\" data-e-type=\"container\" id=\"1\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8d0502c e-con-full e-flex e-con e-child\" data-id=\"8d0502c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-59aaf24 elementor-widget elementor-widget-heading\" data-id=\"59aaf24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Overview<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ee5a12a e-con-full e-flex e-con e-child\" data-id=\"ee5a12a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7b63b42 elementor-widget elementor-widget-text-editor\" data-id=\"7b63b42\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>Semax (ACTH(4\u20137)-PGP; also referenced as Pro-Gly-Pro-ACTH in registry records) is a synthetic heptapeptide derived from a defined segment of adrenocorticotropic hormone (ACTH). In the scientific literature, Semax has been used as a research tool in neurobiology and molecular signaling studies, including investigations of activity-dependent gene programs, neurotrophin-linked transcriptional responses, monoaminergic pathway markers, and systems-level network activity measured with experimental imaging and omics approaches.<\/p><p>Preclinical publications describe Semax-associated changes in transcriptional signatures across CNS-relevant tissues and report modulation of neurotrophin-related gene expression (including BDNF and NGF) in controlled animal and cell-based experimental designs.<\/p><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-805a397 e-flex e-con-boxed e-con e-child\" data-id=\"805a397\" data-element_type=\"container\" data-e-type=\"container\" id=\"2\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-e03ab05 e-con-full e-flex e-con e-child\" data-id=\"e03ab05\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1eea56f elementor-widget elementor-widget-heading\" data-id=\"1eea56f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Biochemical Characteristics\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c9269a6 e-con-full e-flex e-con e-child\" data-id=\"c9269a6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-895d197 elementor-widget elementor-widget-image\" data-id=\"895d197\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"352\" height=\"377\" src=\"https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2026\/01\/semax-structure.webp\" class=\"attachment-full size-full wp-image-1058\" alt=\"\" srcset=\"https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2026\/01\/semax-structure.webp 352w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2026\/01\/semax-structure-280x300.webp 280w\" sizes=\"(max-width: 352px) 100vw, 352px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-313789c elementor-widget elementor-widget-text-editor\" data-id=\"313789c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>Image of Semax without the N-acetyl side chain<br \/>Source:\u00a0<a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/122178\" target=\"_blank\" rel=\"nofollow noopener\">PubChem<\/a><\/p><p><strong>Sequence<\/strong>: Met-Glu-His-Phe-Pro-Gly-Pro<br \/><strong>Molecular Formula<\/strong>: C37H51N9O10S<br \/><strong>Molecular Weight<\/strong>: 813.92 g\/mol<br \/><strong>CAS Number<\/strong>: 80714-61-0<br \/><strong>Synonyms<\/strong>: Pro-Gly-Pro-ACTH<\/p><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-89a922c e-flex e-con-boxed e-con e-child\" data-id=\"89a922c\" data-element_type=\"container\" data-e-type=\"container\" id=\"3\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-f5455f0 e-con-full e-flex e-con e-child\" data-id=\"f5455f0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dd6fbb4 elementor-widget elementor-widget-heading\" data-id=\"dd6fbb4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Research Applications\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cc49a3c e-con-full e-flex e-con e-child\" data-id=\"cc49a3c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f48ec5c elementor-widget elementor-widget-text-editor\" data-id=\"f48ec5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>Semax is a synthetic analogue of an ACTH fragment, corresponding to amino acids 4\u201310 of ACTH with a C-terminal Pro-Gly-Pro motif. In laboratory research, Semax is used in preclinical models to probe pathway-level regulation of:<\/p><ul><li><strong>Neurotrophin-linked transcription:<\/strong>\u00a0experimental readouts involving BDNF and NGF gene-expression dynamics in CNS-relevant regions [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref5\">5<\/a>].<\/li><li><strong>Systems-level brain network activity:<\/strong>\u00a0research imaging endpoints assessing resting-state network behavior and connectivity patterns [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref1\">1<\/a>].<\/li><li><strong>Neurovascular and immune-associated gene programs:<\/strong>\u00a0genome-wide transcriptional profiling in animal models with emphasis on vascular-system and immune-system gene sets in brain tissue [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref3\">3<\/a>].<\/li><li><strong>Learning\/memory model endpoints:<\/strong>\u00a0mechanistic comparisons using ACTH-related peptides in rodent genetic models with cognition-focused behavioral readouts [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref6\">6<\/a>].<\/li><li><strong>Monoaminergic signaling markers:<\/strong>\u00a0studies of serotonergic pathway measures and neurotrophin-dependent behavioral paradigms in rodents [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref7\">7<\/a>].<\/li><li><strong>Oxidative stress biomarker panels:<\/strong>\u00a0liver-associated morphofunctional and lipid peroxidation endpoints under stress-model conditions [8] [9].<\/li><\/ul><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8f12065 e-flex e-con-boxed e-con e-child\" data-id=\"8f12065\" data-element_type=\"container\" data-e-type=\"container\" id=\"4\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-67de5a3 e-con-full e-flex e-con e-child\" data-id=\"67de5a3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-49efd74 elementor-widget elementor-widget-heading\" data-id=\"49efd74\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Preclinical Research Summary\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fddb75a e-con-full e-flex e-con e-child\" data-id=\"fddb75a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d874b6d elementor-widget elementor-widget-text-editor\" data-id=\"d874b6d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p><strong>Pathway \/ Mechanistic Context<\/strong><\/p><p>Across cited preclinical literature, Semax is evaluated as a modulator of gene-expression programs and systems-level neural network activity. Reported endpoints include transcriptomic changes in CNS tissue, neurotrophin-associated transcriptional dynamics, and network-level activity patterns measured by experimental neuroimaging approaches. In addition, publications describe Semax-associated shifts in peripheral oxidative stress biomarker panels and hepatic tissue readouts under stress-model conditions.<\/p><p><strong>1. Resting-State Network Readouts<\/strong><\/p><p>Experimental imaging work reports changes in resting-state network behavior after Semax exposure, including measured effects on the default mode network as defined within that study\u2019s analytic framework [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref1\">1<\/a>]. Background literature on default mode and social-cognition network relationships is commonly used to interpret these kinds of resting-state measures in neuroscience research [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref2\">2<\/a>].<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c9ba48d elementor-widget elementor-widget-image\" data-id=\"c9ba48d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"531\" height=\"579\" src=\"https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2026\/01\/semax-diagram.webp\" class=\"attachment-large size-large wp-image-1059\" alt=\"\" srcset=\"https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2026\/01\/semax-diagram.webp 531w, https:\/\/md.biovantixlab.com\/wp-content\/uploads\/2026\/01\/semax-diagram-275x300.webp 275w\" sizes=\"(max-width: 531px) 100vw, 531px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6f5cfb6 elementor-widget elementor-widget-text-editor\" data-id=\"6f5cfb6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>Image showing the overlap of activation between the resting mode network and parts of the brain responsible social cognition.<br \/>Source:\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3380415\/\" target=\"_blank\" rel=\"nofollow noopener\">PubMed<\/a><\/p><p><strong>2. Genome-Wide Transcriptional Profiling in a Rodent Ischemia Model<\/strong><\/p><p>In a rat model of focal brain ischemia, genome-wide transcriptional analysis reported Semax-associated changes in expression across immune- and vascular-system related gene sets in brain tissue, providing a molecular context for mechanistic investigation of neurovascular and inflammatory pathway regulation in this model [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref3\">3<\/a>].<\/p><p><strong>3. Neurotrophin-Related Gene Expression Dynamics<\/strong><\/p><p>Rodent studies report that Semax exposure is associated with time-dependent gene expression changes in the hippocampus and frontal cortex, including reported effects on BDNF and NGF gene-expression measures within the study design [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref5\">5<\/a>].<\/p><p><strong>4. ACTH-Related Peptides in a Genetic Epilepsy Model<\/strong><\/p><p>Preclinical work in a Kcna1-null mouse model reports that ACTH exposure is associated with preservation of learning and memory readouts in the experimental paradigm, providing comparative context for research on ACTH-derived peptide fragments such as Semax [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref6\">6<\/a>].<\/p><p><strong>5. Serotonergic and Neurotrophin-Linked Behavioral Paradigms<\/strong><\/p><p>Rodent studies evaluating altered hippocampal BDNF levels report behavioral and serotonergic consequences in experimental models, supporting broader mechanistic frameworks that connect neurotrophin abundance, serotonergic pathway markers, and behavioral outputs in preclinical research [<a href=\"https:\/\/www.peptidesciences.com\/semax-30mg?queryID=14fe2cbdf453fdefa40df55301b4e19d&amp;objectID=142&amp;indexName=psm2_default_products#ref7\">7<\/a>].<\/p><p><strong>6. Peripheral Oxidative Stress and Hepatic Biomarker Readouts<\/strong><\/p><p>Additional cited studies describe Semax-associated effects on hepatic morphofunctional endpoints and lipid peroxidation markers in rat stress-model conditions, including biochemical measures relevant to oxidative stress research workflows [8] [9].<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-855637d e-flex e-con-boxed e-con e-child\" data-id=\"855637d\" data-element_type=\"container\" data-e-type=\"container\" id=\"5\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3657e2d e-con-full e-flex e-con e-child\" data-id=\"3657e2d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-902f324 elementor-widget elementor-widget-heading\" data-id=\"902f324\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Preclinical Research Summary\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5e8875f e-con-full e-flex e-con e-child\" data-id=\"5e8875f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7829a1 elementor-widget elementor-widget-text-editor\" data-id=\"c7829a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p align=\"justify\">Preclinical studies cited in the scientific literature describe observations involving MOTS-c in cellular and animal model systems. Reported observations include measurements of signaling-associated proteins, metabolite profiles, and gene expression markers recorded under defined experimental conditions.<\/p><p align=\"justify\">Additional publications describe associations between MOTS-c and molecular features observed in experimental models of metabolic stress and mitochondrial perturbation. All reported findings are restricted to the experimental systems employed.<\/p><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-40ba7b7 e-flex e-con-boxed e-con e-child\" data-id=\"40ba7b7\" data-element_type=\"container\" data-e-type=\"container\" id=\"6\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-fa5e150 e-con-full e-flex e-con e-child\" data-id=\"fa5e150\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d98030c elementor-widget elementor-widget-heading\" data-id=\"d98030c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Form &amp; Analytical Testing\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2f740c1 e-con-full e-flex e-con e-child\" data-id=\"2f740c1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d1c1164 elementor-widget elementor-widget-text-editor\" data-id=\"d1c1164\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tSemax is a synthetic peptide supplied for controlled laboratory workflows. Laboratories may reference sequence, CAS, and registry identifiers for internal documentation and study design. Analytical characterization for peptide materials commonly includes chromatographic purity profiling and mass confirmation consistent with internal qualification standards.\n\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-06bb7a9 e-flex e-con-boxed e-con e-child\" data-id=\"06bb7a9\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3686be8 e-con-full e-flex e-con e-child\" data-id=\"3686be8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1a8031c elementor-widget elementor-widget-heading\" data-id=\"1a8031c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Article Author\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ec485a0 e-con-full e-flex e-con e-child\" data-id=\"ec485a0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-285b1b7 elementor-widget elementor-widget-text-editor\" data-id=\"285b1b7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>The above literature was researched, edited and organized by Dr. Logan, M.D. Dr. Logan holds a doctorate degree from\u00a0<a href=\"https:\/\/case.edu\/medicine\/\" target=\"_blank\" rel=\"nofollow noopener\">Case Western Reserve University School of Medicine<\/a>\u00a0and a B.S. in molecular biology.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a66406b e-flex e-con-boxed e-con e-child\" data-id=\"a66406b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c3d92b2 e-con-full e-flex e-con e-child\" data-id=\"c3d92b2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a069450 elementor-widget elementor-widget-heading\" data-id=\"a069450\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Scientific Journal Author\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1ca5417 e-con-full e-flex e-con e-child\" data-id=\"1ca5417\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d3929fa elementor-widget elementor-widget-text-editor\" data-id=\"d3929fa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p><a href=\"https:\/\/www.researchgate.net\/profile\/Igor_Bobyntsev\" target=\"_blank\" rel=\"nofollow noopener\">Dr. Igor Ivanovich Bobyntsev<\/a>\u00a0researches at the Kursk State Medical University within the Department of Pathophysiology. His main goal is to find new, more effective methods for teaching morphological disciplines\u2026 such as histology, cytology, embryology, human anatomy, pathological anatomy, the study of the morphological manifestation of stress-limiting effects of neuropeptides and their synthetic analogues. His key interests pertain to Antioxidants, Free Radicals, Antioxidant Activity, Free Radical Scavengers, Reactive Oxygen Species, Lipid Peroxidation, SOD, Oxidative Stress Biomarkers, Inflammatory Biomarkers, and Oxidative Stress. He specifically studied the influence of Semax on the morphofunctional state of hepatocytes, and lipid peroxidation in the liver, when under chronic emotional and painful stress.<\/p><p>Dr. Igor Ivanovich Bobyntsev is being referenced as one of the leading scientists involved in the research and development of Semax. In no way is this doctor\/scientist endorsing or advocating the purchase, sale, or use of this product for any reason. There is no affiliation or relationship, implied or otherwise, between Peptide Sciences and this doctor. The purpose of citing the doctor is to acknowledge, recognize, and credit the exhaustive research and development efforts conducted by the scientists studying this peptide. Dr. Igor Ivanovich Bobyntsev is listed in [8] and [9] under the referenced citations.<\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1bfb79d e-flex e-con-boxed e-con e-child\" data-id=\"1bfb79d\" data-element_type=\"container\" data-e-type=\"container\" id=\"7\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-456f1aa e-con-full e-flex e-con e-child\" data-id=\"456f1aa\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-343a28d elementor-widget elementor-widget-heading\" data-id=\"343a28d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Referenced Citations\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4ed0fc7 e-con-full e-flex e-con e-child\" data-id=\"4ed0fc7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e407573 elementor-widget elementor-widget-text-editor\" data-id=\"e407573\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><ol><li id=\"ref1\">I. S. Lebedeva et al., \u201cEffects of Semax on the Default Mode Network of the Brain,\u201d Bull. Exp. Biol. Med., vol. 165, no. 5, pp. 653\u2013656, Sep. 2018. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30225715\" target=\"_blank\" rel=\"nofollow noopener\">PubMed<\/a>]<\/li><li id=\"ref2\">R. B. Mars, F.-X. Neubert, M. P. Noonan, J. Sallet, I. Toni, and M. F. S. Rushworth, \u201cOn the relationship between the \u2018default mode network\u2019 and the \u2018social brain,\u2019\u201d Front. Hum. Neurosci., vol. 6, 2012. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3380415\/\" target=\"_blank\" rel=\"nofollow noopener\">PMC<\/a>]<\/li><li id=\"ref3\">E. V. Medvedeva et al., \u201cThe peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis,\u201d BMC Genomics, vol. 15, p. 228, Mar. 2014. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24661604\" target=\"_blank\" rel=\"nofollow noopener\">PubMed<\/a>]<\/li><li id=\"ref4\">E. I. Gusev, M. Y. Martynov, E. V. Kostenko, L. V. Petrova, and S. N. Bobyreva, \u201c[The efficacy of semax in the tretament of patients at different stages of ischemic stroke],\u201d Zh. Nevrol. Psikhiatr. Im. S. S. Korsakova, vol. 118, no. 3. Vyp. 2, pp. 61\u201368, 2018. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29798983\/\" target=\"_blank\" rel=\"nofollow noopener\">PubMed<\/a>]<\/li><li id=\"ref5\">T. I. Agapova et al., \u201c[Effect of semax on the temporary dynamics of brain-derived neurotrophic factor and nerve growth factor gene expression in the rat hippocampus and frontal cortex],\u201d Mol. Genet. Mikrobiol. Virusol., no. 3, pp. 28\u201332, 2008. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18756821\" target=\"_blank\" rel=\"nofollow noopener\">PubMed<\/a>]<\/li><li id=\"ref6\">M. H. Scantlebury, K.-C. Chun, S.-C. Ma, J. M. Rho, and D. Y. Kim, \u201cAdrenocorticotropic Hormone Protects Learning and Memory Function in Epileptic Kcna1-null mice,\u201d Neurosci. Lett., vol. 645, pp. 14\u201318, Apr. 2017. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28249786\" target=\"_blank\" rel=\"nofollow noopener\">PubMed<\/a>]<\/li><li id=\"ref7\">T. Deltheil et al., \u201cBehavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice,\u201d Neuropharmacology, vol. 55, no. 6, pp. 1006\u20131014, Nov. 2008. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18761360\" target=\"_blank\" rel=\"nofollow noopener\">PubMed<\/a>]<\/li><li>Ivanov, Alexander &amp; Bobyntsev, Igor &amp; Shepeleva, Olga &amp; Kryukov, Alexey &amp; Andreeva, L &amp; Myasoedov, N. (2017). Influence of ACTG4-7-PGP (Semax) on Morphofunctional State of Hepatocytes in Chronic Emotional and Painful Stress. Bulletin of experimental biology and medicine. 163. [<a href=\"https:\/\/www.researchgate.net\/publication\/317341399_Influence_of_ACTG4-7-PGP_Semax_on_Morphofunctional_State_of_Hepatocytes_in_Chronic_Emotional_and_Painful_Stress\" target=\"_blank\" rel=\"nofollow noopener\">Research Gate<\/a>]<\/li><li>Bobyntsev, Igor &amp; Kryukov, Alexey &amp; Shepeleva, Olga &amp; Ivanov, Alexander. (2015). The effect of ACTH-4-7-PGP peptide on lipid peroxidation in liver and activity of serum transaminases in rats under acute and chronic immobilization stress conditions. 78. 18-21. [<a href=\"https:\/\/www.researchgate.net\/publication\/287223828_The_effect_of_ACTH-4-7-PGP_peptide_on_lipid_peroxidation_in_liver_and_activity_of_serum_transaminases_in_rats_under_acute_and_chronic_immobilization_stress_conditions\" target=\"_blank\" rel=\"nofollow noopener\">Research Gate<\/a>]<\/li><\/ol><p><strong>ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.<\/strong><\/p><\/div><\/div><div class=\"c-pdp-contents__item\">\u00a0<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5a185c5 e-flex e-con-boxed e-con e-child\" data-id=\"5a185c5\" data-element_type=\"container\" data-e-type=\"container\" id=\"8\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8f74d1a e-con-full e-flex e-con e-child\" data-id=\"8f74d1a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bbf522b elementor-widget elementor-widget-heading\" data-id=\"bbf522b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">RUO Disclaimer\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5f8520a e-con-full e-flex e-con e-child\" data-id=\"5f8520a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e04b758 elementor-widget elementor-widget-text-editor\" data-id=\"e04b758\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"s-pdp column main\"><div class=\"s-main-page-grid__container\"><div class=\"s-main-page-grid__content\"><div class=\"s-pdp__contents-wrapper c-pdp-contents\"><div class=\"product info detailed l-page__container\"><div class=\"product product-tab-wrapper mage-tabs-disabled\"><div class=\"product-tab-contents\"><div id=\"product.info.description\" class=\"product-tab-content\" role=\"tabpanel\" aria-labelledby=\"tab-label-product.info.description\" data-role=\"content\" aria-hidden=\"false\"><div class=\"l-page__container description\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div class=\"s-pdp column main\"><div class=\"s-main-page-grid__container\"><div class=\"s-main-page-grid__content\"><div class=\"s-pdp__contents-wrapper c-pdp-contents\"><div class=\"product info detailed l-page__container\"><div class=\"product product-tab-wrapper mage-tabs-disabled\"><div class=\"product-tab-contents\"><div id=\"product.info.description\" class=\"product-tab-content\" role=\"tabpanel\" aria-labelledby=\"tab-label-product.info.description\" data-role=\"content\" aria-hidden=\"false\"><div class=\"l-page__container description\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><div id=\"product.info.description\" class=\"product-tab-content\" role=\"tabpanel\" aria-labelledby=\"tab-label-product.info.description\" data-role=\"content\" aria-hidden=\"true\"><div class=\"l-page__container description\"><div class=\"c-pdp-contents__item\"><div class=\"c-pdp-contents__text\"><p>The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.<\/p><p><strong>For Laboratory Research Only. Not for human use, medical use, diagnostic use, or veterinary use.<\/strong><\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-1048950752\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1048950752\" data-tab-index=\"2\" style=\"--n-tabs-title-order: 2;\" class=\" elementor-element elementor-element-974752e e-flex e-con-boxed e-con e-child\" data-id=\"974752e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-83b86b7 elementor-widget elementor-widget-text-editor\" data-id=\"83b86b7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<table><tbody><tr><th colspan=\"2\">Properties<\/th><\/tr><tr><td>Molecular Formula<\/td><td>C<sub>37<\/sub>H<sub>51<\/sub>N<sub>9<\/sub>O<sub>10<\/sub>S<\/td><\/tr><tr><td>Molecular Weight<\/td><td>813.9<\/td><\/tr><tr><td>Monoisotopic Mass<\/td><td>813.34796003<\/td><\/tr><tr><td>Polar Area<\/td><td>312<\/td><\/tr><tr><td>Complexity<\/td><td>1450<\/td><\/tr><tr><td>XLogP<\/td><td>-2.8<\/td><\/tr><tr><td>Heavy Atom Count<\/td><td>57<\/td><\/tr><tr><td>Hydrogen Bond Donor Count<\/td><td>8<\/td><\/tr><tr><td>Hydrogen Bond Acceptor Count<\/td><td>13<\/td><\/tr><tr><td>Rotatable Bond Count<\/td><td>21<\/td><\/tr><tr><td>PubChem LCSS<\/td><td><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/9811102#datasheet=LCSS\" target=\"_blank\" rel=\"noopener\">ACTH (4-7), Pro-Gly-Pro- Laboratory Chemical Safety Summary<\/a><\/td><\/tr><\/tbody><\/table><table><tbody><tr><th colspan=\"2\">Identifiers<\/th><\/tr><tr><td>CID<\/td><td>9811102<\/td><\/tr><tr><td>InChI<\/td><td>InChI=1S\/C37H51N9O10S\/c1-57-16-13-24(38)32(50)42-25(11-12-31(48)49)33(51)43-26(18-23-19-39-21-41-23)34(52)44-27(17-22-7-3-2-4-8-22)36(54)46-15-5-9-28(46)35(53)40-20-30(47)45-14-6-10-29(45)37(55)56\/h2-4,7-8,19,21,24-29H,5-6,9-18,20,38H2,1H3,(H,39,41)(H,40,53)(H,42,50)(H,43,51)(H,44,52)(H,48,49)(H,55,56)\/t24-,25-,26-,27-,28-,29-\/m0\/s1<\/td><\/tr><tr><td>InChIKey<\/td><td>AFEHBIGDWIGTEH-AQRCPPRCSA-N<\/td><\/tr><tr><td>Isometric SMILES<\/td><td>CSCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N3CCC[C@H]3C(=O)NCC(=O)N4CCC[C@H]4C(=O)O)N<\/td><\/tr><tr><td>Canonical SMILES<\/td><td>CSCCC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC2=CC=CC=C2)C(=O)N3CCCC3C(=O)NCC(=O)N4CCCC4C(=O)O)N<\/td><\/tr><tr><td>IUPAC Name<\/td><td>(2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-4-carboxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid<\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-1048950753\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1048950753\" data-tab-index=\"3\" style=\"--n-tabs-title-order: 3;\" class=\" elementor-element elementor-element-532f572 e-flex e-con-boxed e-con e-child\" data-id=\"532f572\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5986954 elementor-widget elementor-widget-text-editor\" data-id=\"5986954\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h4>Storage Instructions:<\/h4><p>All of our products are manufactured using the\u00a0<strong>Lyophilization (Freeze Drying)<\/strong>\u00a0process, which ensures that our products remain\u00a0<strong>100% stable for shipping<\/strong>\u00a0for up to\u00a0<strong>3-4 months<\/strong>.<br \/>Once the peptides are\u00a0<strong>reconstituted (mixed with bacteriostatic water)<\/strong>, they must be\u00a0<strong>stored in the fridge<\/strong>\u00a0to maintain stability. After reconstitution, the peptides will remain\u00a0<strong>stable for up to 30 days<\/strong>.<\/p><p>Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you&#8217;re ready to reconstitute it with bacteriostatic water.<\/p><p>Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable.\u00a0Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.<\/p><p>However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide\u2019s stability.<\/p><p>For further information on proper storage techniques,\u00a0click\u00a0the link below:<\/p><p><blockquote class=\"wp-embedded-content\" data-secret=\"M2fHeUiDg3\"><a href=\"https:\/\/biovantixlab.com\/peptide-storage\/\">Peptide Storage<\/a><\/blockquote><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; visibility: hidden;\" title=\"&#8220;Peptide Storage&#8221; &#8212; BioVantix\" src=\"https:\/\/biovantixlab.com\/peptide-storage\/embed\/#?secret=7Uzk2IMXaF#?secret=M2fHeUiDg3\" data-secret=\"M2fHeUiDg3\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the ACTH(4\u201310) fragment. It is widely used in research investigating neurotrophic and nootropic signaling through the modulation of brain-derived neurotrophic factor (BDNF), TrkB, and neurogenic transcription factors such as nerve growth factor (NGF) and growth-associated protein 43 (GAP-43). Experimental data indicate that Semax may influence redox balance, neuronal plasticity, and dopaminergic regulation in central nervous system (CNS) models.<\/p>\n<p>For research use only. Not for human consumption.<\/p>\n<p><strong>References:<\/strong><br \/>\nAshmarin IP et al., <em>Neuroscience and Behavioral Physiology<\/em>, 1998;28(3):341\u2013348<br \/>\nAshmarin IP et al., <em>Neurochemical Journal<\/em>, 2005;39(1):36\u201344<br \/>\nDolotov OV et al., <em>Brain Research Bulletin<\/em>, 2011;85(5):327\u2013332<\/p>\n","protected":false},"featured_media":1692,"template":"","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the ACTH(4\u201310) fragment. It is widely used in research investigating neurotrophic and nootropic signaling through the modulation of brain-derived neurotrophic factor (BDNF), TrkB, and neurogenic transcription factors such as nerve growth factor (NGF) and growth-associated protein 43 (GAP-43). Experimental data indicate that Semax may influence redox balance,&hellip;","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=\/wp\/v2\/product\/1050","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"version-history":[{"count":15,"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=\/wp\/v2\/product\/1050\/revisions"}],"predecessor-version":[{"id":1693,"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=\/wp\/v2\/product\/1050\/revisions\/1693"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=\/wp\/v2\/media\/1692"}],"wp:attachment":[{"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1050"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=1050"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=1050"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/md.biovantixlab.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=1050"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}